Dose calculator

Melanotan-2 dose calculator

Convert any Melanotan-2 dose into syringe units in real time, pre-filled with a 10 mg / 2 mL example.

iPhone · Free to download

Last updated: May 13, 2026

Vial (mg)

Diluent (mL)

Dose (mg)

Dose unit

Draw on a U-100 syringe

10.0 units

Volume to draw

0.100 mL

Melanotan 2 is a peptide people inject to develop a deeper tan with less sun exposure by activating the body's own pigment-producing cells. It binds to melanocortin receptors that signal melanocytes to make more melanin, and it can also trigger libido effects as a side effect. In small studies, users developed visibly darker skin within 2–4 weeks of consistent low-dose use. This page covers reconstitution math and how people typically log a loading-then-maintenance schedule.

How the Melanotan-2 dose calculator works

Melanotan-2 doses start at 0.25 mg daily for tan-response loading, then drop to maintenance. On a 10 mg vial mixed with 2 mL water (5 mg/mL), a 0.5 mg dose draws 10 units. Loading-phase users build up over 2-3 weeks before easing off.

The formula is volume in mL equals dose mg divided by concentration mg/mL, then volume times one hundred to get units on a U-100 insulin syringe. With a 5 mg/mL Melanotan-2 solution and a 0.5 mg dose, the draw is 0.10 mL or about 10 units. Type any other dose and the unit count updates in real time — no spreadsheets, no guesswork.

Inputs that genuinely matter: concentration (which only changes when you reconstitute a new vial) and dose mass. Syringe type matters too, but only because U-100 vs U-40 changes the multiplier — almost every modern insulin syringe is U-100, which is why the math defaults to that. Edge cases worth flagging: switching from mcg to mg without checking the input unit, or carrying yesterday's unit count over to a new vial that was reconstituted with a different volume of BAC water.

Worked example

Walking one Melanotan-2 dose through the math

The vial holds 10 mg of Melanotan-2, mixed into 2 mL of bacteriostatic water — concentration 5.00 mg/mL.
Your 0.5 mg dose ÷ 5.00 mg/mL = 0.100 mL of solution to pull.
Multiply by 100 (because U-100 means 100 units per mL): 0.100 × 100 = 10 units.
Double the dose to 1 mg and the unit count doubles to 20 — the relationship is linear at a fixed concentration.
Change the diluent volume and every one of these numbers moves; change the dose alone and only the last one does.

Melanotan-2 titration ladder at this concentration

What different Melanotan-2 dose steps draw on a U-100 insulin syringe at the example 5.00 mg/mL concentration.

Dose (mg)	Volume (mL)	Units (U-100)
0.25	0.050	5
0.5	0.100	10
1	0.200	20
2	0.400	40

Doubling the Melanotan-2 dose doubles the unit count. Halving it halves the count. Step-ups under 5 units are hard to read accurately — re-reconstitute with more water if your titration hits that range.

Scenarios people actually run into

Three things that come up logging Melanotan-2

You're sitting at the 0.5 mg Melanotan-2 step and your prescriber bumps you up. The new dose is double — 20 units instead of 10. Same vial, same syringe, twice the volume on the line.
Your fingers reach for the syringe and the unit count from last week is still in your head. Half the time that number is fine; the other half, the vial changed and the right answer moved. The calculator is the second pair of eyes.
You skipped a week. Melanotan-2 cadence is 7 doses per week, and doubling up to "catch up" almost never reads how people expect — log the skip, then log the next normal dose.

Same-category neighbor

Melanotan-2 next to Tirzepatide

Both sit in the Melanocortin bucket — here's the dose math side by side on each one's example vial.

	Melanotan-2	Tirzepatide
Example dose	0.5 mg	2.5 mg
Concentration	5.00 mg/mL	5.00 mg/mL
Units to draw	10	50

Want the full breakdown? Tirzepatide reference →

How Melanotan-2 dosing is tracked

Loading-phase protocols are typically daily; maintenance-phase protocols are less frequent. Recording the transition from loading to maintenance explicitly in the log is what makes the phase change auditable later.

A common protocol structure documented in personal logs for Melanotan-2 involves two distinct phases: a 'loading' phase and a 'maintenance' phase. The initial loading phase typically consists of small, frequently administered doses. Users may plan to schedule these administrations daily or every other day over a period of 7 to 21 days. The objective from a data-logging perspective is not simply to document the passage of time, but to track the cumulative dose required to reach a specific, observable endpoint. Meticulously recording each administration during this period allows for a granular analysis of the dose-response relationship unique to the individual.

Upon reaching the desired response level, users typically transition to a maintenance phase. This involves adjusting the schedule to a less frequent cadence, such as once or twice per week, to sustain the observed state. The dose amount may also be adjusted during this phase. Logging the specific date of this transition is one of the most critical data entry points for any long-term tracking plan. This marker allows calculation tools to properly attribute dosage and observations to either the initial accumulation period or the subsequent sustainment period, providing a clear and auditable record for personal review.

Common Melanotan-2 dose-calculation mistakes

Continuing a loading-phase dose into what should have been the maintenance phase because no transition was recorded.
Assuming a linear response to each individual dose rather than scheduling and tracking the cumulative dose over a defined loading phase.
Failing to document an adjusted, higher-volume reconstitution plan, leading to significant errors in dose calculation when converting from units to milligrams.

Frequently asked questions about Melanotan-2 dose calculator

How does the Melanotan-2 dose calculator turn mg into syringe units?

It runs two divisions in sequence. First it computes concentration (vial mg ÷ diluent mL) — for the example here that's 10 ÷ 2 = 5.00 mg/mL. Then it divides your dose by that concentration to get volume in mL, and multiplies by 100 to convert volume into U-100 syringe units. The output updates as you type so you can sanity-check before drawing. Melanotan-2 loading typically ramps from 0.25 mg up to 1 mg over 2-3 weeks, then drops to 1-2 maintenance doses per week.

Does the Melanotan-2 dose calculator know which syringe I'm using?

It assumes a U-100 insulin syringe — the most common type for sub-cutaneous peptide injections. U-100 means 100 units per mL. If you're using a U-40 syringe (rare outside veterinary contexts) the unit count is wrong by a factor of 2.5. Tuberculin syringes read in mL directly, so on those just use the volume figure. Melanotan-2 loading typically ramps from 0.25 mg up to 1 mg over 2-3 weeks, then drops to 1-2 maintenance doses per week.

Why does the same Melanotan-2 dose pull a different unit count today than last week?

Because either the vial or the diluent volume changed. Concentration depends on both. A 5 mg vial reconstituted with 1 mL is twice as concentrated as the same vial with 2 mL — same dose, half the units. Whenever you open a fresh vial, run the dose math again rather than carrying the prior count over. Melanotan-2 loading typically ramps from 0.25 mg up to 1 mg over 2-3 weeks, then drops to 1-2 maintenance doses per week.

What if my Melanotan-2 dose lands at fewer than 5 units?

That's the calculator telling you the current vial is too concentrated for the dose you want. Five units on a U-100 syringe is hard to read accurately — the markings get tight. Reconstitute the next vial with more bacteriostatic water (commonly 2 mL instead of 1 mL) so each dose covers a larger, cleaner volume. Melanotan-2 loading typically ramps from 0.25 mg up to 1 mg over 2-3 weeks, then drops to 1-2 maintenance doses per week.

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